FREE Shipping on orders over $25 shipped by Amazon. Each vial contains 12.5 grams of sodium thiosulfate in 50 mL solution (250 mg/mL). Common side effects of sodium thiosulfate include nausea, vomiting, headache, low blood pressure (hypotension), salty taste in the mouth, warm sensation over the body, prolonged bleeding time, hypersensitivity reactions, local irritation, and contact dermatitis. The usual dosage is a capful per 10 gallons. Sodium thiosulfate injection is a sterile aqueous solution and is intended for intravenous injection. This product is used in water treatment for removing excess of chlorine. Sodium thiosulfate is a common dechlorinator used to remove chlorine from drinking water. Some people who take too much apricot pits (cancer treatment) have a weak form of cyanide poisoning and found it helpful to . Drugs & Vitamins Drugs A-Z Generic Drugs A-Z Drugs by Classification Drugs Comparison (Drug Vs. 35, 36 STS is an antidote for cyanide and cisplatin toxicity and has antioxidant properties. Sodium Thiosulfate is a very common de-chlorinator in the aquarist industry. PEDMARK is contraindicated in patients with a history of severe hypersensitivity to sodium thiosulfate or its components [see Contraindications (4)]. Among patients who respond, we extend the . For . The hypothesis of this study is that local administration of sodium thiosulfate (STS) will result in improved hearing compared to ears not receiving the study drug in patients . CAS Number: 10102-17-7. In emergency disinfection with . Metallic gold is known for its electrochemical nobility, and resulting lack of reactivity. DOCUMENTATION. 40 / Kilogram. Sodium thiosulfate | Na2S2O3 or Na2O3S2 | CID 24477 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . Its use was subsequently proposed for tumoral calcinosis in renal failure ( 10) and the first report of its use for CUA appeared almost a . I learned of sodium thiosulfate from a candida protocol in the book: Candida--Killing So Sweetly, by Bill Thompson. Sodium thiosulfate 99.99% trace metals basis; CAS Number: 7772-98-7; EC Number: 231-867-5; Synonyms: Disodium thiosulfate,Disodium thiosulphate,Sodium hyposulfite,Sodium oxide sulfide (Na2S2O3 ),Sodium thiosulfate,Sodium thiosulfate (Na2 S2 O3 ),Sodium thiosulfate anhydrous,Sodium thiosulphate,Sulfothiorine,Thiosulfuric acid, disodium salt; Linear Formula: Na2S2O3; find Sigma-Aldrich-563188 . Sodium Thiosulfate Injection should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is frequently used after the drug sodium nitrite for cyanide poisoning and is usually only prescribed in severe situations. This product is available in the following dosage forms: Solution; Before Using. Sodium Thiosulphate: An Overview. For cyanide poisoning it is often used after the medication sodium nitrite and typically only recommended for severe cases. Simply add 2 drops of the stock solution per 1 gallon of the body of water to be treated . One such therapy that is now commonly used in CUA is sodium thiosulfate (STS). The incidence of hearing loss was lower in the sodium thiosulfate and cisplatin arm (39%) compared with the cisplatin alone arm (68%); unadjusted relative risk 0.58 (95% CI: 0.40, 0.83). 5H 2 O. Sodium Thiosulfate, Pentahydrate Safety Data Sheet according to Federal Register / Vol. Sodium Thiosulfate is used as a dechlorination agent. Sodium thiosulphate (sodium thiosulfate) is an inorganic chemical compound described with the formula Na 2 S 2 O 3.It is mostly found in the pentahydrate form, hence, referred with the chemical formula Na 2 S 2 O 3.5H 2 O. will give a final concentration of 18 mg/L in the. If you have questions about side effects, call your doctor. Systemic sodium thiosulfate therapy is commonly used to treat calciphylaxis in patients with renal disorders with very few adverse events (1). Contact Supplier. Headache . On the basis of the nonrenal clearance and the thiosulfate steady-state serum concentrations, a mean endogenous thiosulfate generation rate of 14.6 nmol/min per kg was calculated in patients. It is usually 12 grams per square meter of body surface area, injected into a vein over a period of six hours. Sodium thiosulfate therapy was resumed, and pain and skin lesions again resolved within 2 and 12 weeks, respectively. ORDER MINIMUM- There is a minimum total order value of $10.00 excluding shipping and handling. Pay $10.50 for ground shipping on orders under $175. Liquid phosgene is assayed by an iodometric method which iavolves the foUowiag reaction (52). Thus, it is usually accepted to be a non-allergenic metal. If you order less than $10 in product, we will round the price up to $10 + S/H. I have it under pretty good authority that Sodium Thiosulfate when added to water with chloramine will release ammonia. Sodium thiosulfate has many roles including being used as an antidote to cyanide poisoning as well as an antifungal drug. Technical Grade Crystals Sodium Thiosulphate Crystal, For Laboratory, Packaging Size: 30 Kg,50 Kg. Sodium Thiosulphate is usually prepared by heating sulfur along with aqueous sodium hydroxide solution or by using aqueous sodium sulfite solution. A search of the literature to date yields no formal studies that aim to determine whether topical sodium thiosulfate is truly an effective therapy for calcinosis cutis. One patient, a 57-year-old woman with end- This is a decision you and your doctor will make. Learn about side effects, dosages, drug interactions, and more. Please call for questions or technical assistance! Sodium thiosulfate is a moderately hazardous compound if it is inhaled or ingested, and it can be a slight irritant when it comes in contact with the eyes or skin. She noted that hearing . Storage Code: Greengeneral chemical storage. Shakti Chemicals. Formula: Na 2 S 2 O 3 5H 2 O. Sodium Thiosulphate Crystals. Photography as a fixing agent (hypo) to dissolve unchanged silver salts from exposed negatives. It is a large crystaline product that is readily soluble in water. Identification Consult your doctor if pregnant or breastfeeding. It is also known to limit adverse effects of certain chemotherapies such as cisplatin . It also removes heavy metals. CAS: 7772-98-7: Molecular Formula: H10Na2O8S2: Molecular Weight (g/mol) 248.17: MDL Number: MFCD00003499: InChI Key: PODWXQQNRWNDGD-UHFFFAOYSA-L: Synonym: sodium . Sodium Thiosulfate, Pentahydrate (10102 -17 -7) Our Safe DChlor T-Series TABLETS are used for professional and environmental applications. Monitor patients for hypersensitivity reactions. A variety of therapies have been reported, with limited success, including the treatment of CC with the use of . Sodium Thiosulfate, Packaging Size: Upto 800g. Small Business. SDS; CoA; Synonyms: Antichlor CAS #: 7772-98-7 EC Number: 231-867-5 Molar Mass: 158.10 g/mol Hill Formula: NaOS . Cleaning A mixture of 1 tsp sodium thiosulfate and cup warm water is a useful recipe for cleaning Betadine or iodine spills on fabric. Sodium thiosulfate is a medication used as an antidote to cyanide poisoning. Products Home SODIUM THIOSULFATE PENTAHYDRATE HP. STS in the blood binds to the calcium phosphate and other calcium salts to form calcium thiosulfate. Sodium thiosulfate, 0.1 N standard solution Revision Date 24-Dec-2021 Component CAS No Weight % Water 7732-18-5 97.5 Sodium thiosulfate 7772-98-7 2.5 4. Sodium Thiosulfate Flinn Scientific, Inc. P.O. The drug sodium thiosulfate can protect the hearing of children with cancer undergoing treatment with the chemotherapy drug cisplatin, results from a new study show.. One study found that omitting sodium thiosulfate during sample collection resulted in false negative readings of legionella in hot water supplies held for 30 minutes before analysis (Wiedenmann et al. For cyanide poisoning: Adults and teenagersThe usual dose is 12.5 grams injected into a vein at a rate of 0.625 to 1.25 grams (2.5 to 5 milliliters [mL]) per minute. To the Editor: Calcinosis cutis (CC) is a rare cutaneous condition defined by abnormal depositions of insoluble calcium salts in the skin and subcutaneous tissue.1 Finding effective and safe treatments for these calcified lesions has been a known challenge among dermatologists. Sodium thiosulfate is to be administered only by or under the immediate supervision of your doctor. This product is available in the following . Formula Weight: 248.19. Double the dosage and it also removes chloramine. First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. It is either given by injection into a vein or applied to the skin. Upset stomach or throwing up. 2001). It is also used with another medicine in the emergency treatment of cyanide poisoning. The solubility of calcium thiosulfate in aqueous solutions can mobilize calcium from ectopic sources. If using 25 percent sodium thiosulfate, mix 1.6 mL with 8.4 mL of sterile water for injection . SODIUM THIOSULFATE PENTAHYDRATE HP. Bad taste in your mouth. Sodium thiosulfate is a common dechlorinator used to remove chlorine from drinking water. Sodium thiosulfate (STS) (Na 2 S 2 O 3) is used to prevent and treat cyanide poisoning . Sodium Thiosulfate, Pentahydrate (10102 -17 -7) LC50 fish 1 10000 Sodium Carbonate, Anhydrous (497 -19 -8) LC50 fish 1 300 mg/l EC50 Daphnia 1 265 mg/l LC50 fish 2 740 mg/l 12.2. While reviewing the instructions, you can learn about the therapeutic properties of sodium thiosulfate: stops the inflammatory process; Descriptions. Synonyms: Sodium hyposulfite. Get medical attention. This is a decision you and your doctor will make. make a 4 percent solution: If using 10 percent sodium thiosulfate, mix 4 mL with 6 mL of sterile water for injection. Pool Dechlorinator Sodium Thiosulfate Pentahydrate 5 lbs by Cesco Solutions - Premium Chlorine Neutralizer for Pools, Aquarium, Pond - Technical-Grade Chlorine Remover for Hot Tubs - Bulk Package. 50lb Sodium Thiosulfate Chlorine Neutralizer Additional Information SDS . MAIN USES Chlorine removal. It was originally used as an intravenous medication for metal poisoning. Some people who take too much apricot pits (cancer treatment) have a weak form of cyanide poisoning and found it helpful to . Sodium thiosulfate, also denoted as sodium thiosulphate, is a colorless crystalline compound. You may report side effects to the FDA at 1-800-332-1088. 0 Reviews Hide Reviews Show Reviews . 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 03/07/2005 Revision date: 04/25/2018 Supersedes: 07/09/2013 Version: 1.1 04/25/2018 EN (English US) Page 1 SECTION 1: Identification 1.1. expand to see full list. There are case reports of using sodium thiosulfate (STS) with apparent healing of the ulcers. Add 4 ounces Sodium Thiosulfate to 1 gallon of water. Sodium thiosulfate 500 mg/kg provided a 5% protection. SODIUM THIOSULFATE (SOE dee um thi oh SUHL feyt) is used to treat cyanide poisoning. The patient's previously elevated serum calcium and C-reactive protein levels gradually decreased. It is also a protective medicine used to prevent or lessen the kidney damage that can be caused by cisplatin chemotherapy. Sodium thiosulfate is to be administered only by or under the immediate supervision of your doctor. Do not treat a poisoning or overdose yourself. Seller was quick to answer how to create the 10%; it'the ratio by weight (1:9 . It is an ionic compound formed by two sodium cations (Na + ) And the negatively charged thiosulfate anion (S 2 OR 3 - ), In which the central sulfur atom is attached to three atoms of oxygen and another atom of sulfur (hence the prefix uncle), through single . Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-10372 Sodium Thiosulfate is a toxin with a modest toxicity . The released iodine is titrated with sodium . As a result, patients are often . "The approval is excellent news for children with cancer and their families," said Dr. Cunningham. The. Extravasation injury from chemotherapy and other non-antineoplastic vesicants. For swimming pools, sodium thiosulfate is used as a reagent in the testing of pool water, primarily to . In the oil and gas industry, sodium or ammonium thiosulfate can be used to improve thermal stability of fluidized polymer suspensions. solution of Sodium thiosulfate in a 120-mL bottle. Sodium Thiosulfate manufacturers, service companies and distributors are listed in this trusted and comprehensive vertical portal. Before using sodium thiosulfate. 77, No. Alpha-ketoglutaric acid (250 mg/kg) and sodium thiosulfate (1000 mg/kg) provided an additional 48% protection against a LCT88 of HCN. By definition, sodium thiosulfate is an inorganic sodium salt made of sodium and thiosulfate ions. The addition of sodium thiosulfat. The invention discloses a method for crystallizing sodium thiosulfate pentahydrate, which particularly comprises the following steps of: continuously feeding sodium thiosulfate solution with the concentration of less than 51Be' into an Oslo cooling crystallizer and continuously feeding the obtained solution into a heat exchanger through a circulating pump for the cooling and temperature . 468. Due to its acronym hypo becoming more popular, its common name is still hypo today.. The structure of thiosulfuric acid shows that the solid also occurs in a monoclinic crystalline structure. This therapy stems from observations published over 3 decades ago that STS could prevent recurrent kidney stone formation ( 9 ). Safe DChlor Tablets are designed for collection containers from 100-1,000ml. Sodium Thiosulfate and Cisplatin-Induced Hearing Loss Cisplatin is an effective treatment for hepatoblastoma but often leads to lifelong irreversible hearing loss. Partially concentrate the resulting solution in the rotary evaporator to reach a third or quarter of the starting volume. Tnompson recommends 6-10 drops of 10% solution. Contact Supplier. This Thermo Scientific brand product was originally part of the Alfa Aesar product . 20 / Kilogram. Use Add 1 drop of concentrate per gallon of water to be treated Be the first to leave a comment for this product. However, when these doses of alpha-ketoglutaric acid and sodium thiosulfate were combined, protection was increased by 18%. It will also from soluble complexes with certain heavy metals facilitating their removal from industrial waste effluents. Sodium thiosulfate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. Feeling of warmth. 714-564-9100 . Each mL also contains 2.8 mg boric acid and 4.4 mg of potassium chloride. The comprehensive directory provides access to full contact and ability information for sourcing professionals, engineers and researchers wishing to get information on Sodium Thiosulfate. Aquariums and pond water treatments as a chlorine remover (see below). For our purposes in the pool, sodium thiosulfate is used to reduce the amount of chlorine. ChildrenThe usual dose is 412.5 milligrams (mg) per kilogram . with sodium thiosulfate treatment of calciphylaxis in hemodialysis patients. Sodium thiosulfate is the first FDA-approved treatment that can reduce the likelihood that a child will experience cisplatin-induced hearing loss as well as the severity of any damage to the inner ear that may occur. This is a 13% solution. Treatment with sodium thiosulfate was continued for 8 months. Sodium thiosulfate is a combined pharmaceutical agent that belongs to a group of antidote drugs (specific antidotes, anti-toxic drugs). Thiosulphate is not a toxic material, and thus . Sodium thiosulfate, 30% is commonly used to dechlorinate water. Sodium thiosulfate is a whitish translucent crystalline compound that is known to be soluble in water. Specifications. There are no reported epidemiological studies of congenital anomalies in infants born to women treated with sodium thiosulfate during pregnancy. It does have two medical uses . Due to the ubiquity of the sodium thiosulfate recommendation, few recent studies have investigated the effects of dechlorination. Sodium Thiosulfate is used to treat acute cyanide poisoning. Purity is important with this product for personal use. Sodium Thiosulfate. These include cyanide poisoning, calciphylaxis, and cisplatin toxicity. Because CC is a rare condition, there is a significant absence of controlled clinical trials on its treatment and, the available data for all suggested therapies are generally reported in case reports or small case series.4 Sodium thiosulfate (STS) is an inorganic salt, which increases calcium solubility and has been reported to be helpful in . It has since been approved for the treatment of certain rare medical conditions. If a poisoning or overdose occurs, get emergency help. The clinical trial involved children with liver cancer that had not spread (localized cancer), for whom cisplatin is the standard chemotherapy.Although cisplatin is very effective, it also causes hearing loss in many children. Shalibhadra Dyechem Private Limited. Calcium thiosulfate, being many folds more . It is used as a titrant in iodometry. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call . Sodium thiosulfate is to be administered only by or under the immediate supervision of your doctor. Hemodialysis clearance of STS was 2.62 1.01 ml/min per kg. Thiosulfate helps rid the body of harmful and toxic compounds. This medicine may be used for other . Get FREE ground shipping on all orders $175+*. Gold (Gold Sodium Thiosulfate) Allergy. Sodium thiosulfate: At the beginning of the development of the chemical, the formula of this additive was considered Na 2 S 2 O 4 and was named sodium hypo-sulfate.The short name is called Hypo.Later its formula Na 2 S 2 O 3 was established. Sodium thiosulfate Preparation: Sulfur is boiled with caustic soda . Add saturated sodium thiosulfate to the cold crude reaction until complete discoloration of the aqueous solution occurs. Return Policy: If for any reason you are not satisfied with this item, it is eligible for a return, exchange, refund, or . Each teaspoonful [5 cc] will contain 650mg active Sodium Thiosulfate. 6NaOH + 4S Na2S2O3 + 2Na2S + 3H2O. It is also a well known antidote for cyanide poisoning where the sodium thiosulfate reacts with cyanide to form sodium thiocyanate. The meaning of SODIUM THIOSULFATE is a hygroscopic crystalline salt Na2S2O3 used especially as a photographic fixing agent and a reducing or bleaching agent called also fixer, hypo. Sodium thiosulfate, 30% . $2199 ($0.27/Ounce) Get it as soon as Tue, Oct 4. Dechlorination tablets (sodium thiosulfate) are used to remove residual chlorine (chloramines) from chlorinated water. After oral application, only 4% of STS was recovered in urine of volunteers, reflecting a . The pH of the solution is adjusted with boric acid and/or sodium hydroxide. Sodium thiosulfate, also spelled sodium thiosulphate, is used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Hemodialysis with STS containing dialysate does result in transfer of STS to the blood compartment. Sodium thiosulfate, commonly known as sodium thiosulphate, is a medicine that is used to treat cyanide poisoning, pityriasis versicolor, and cisplatin side effects. More recently, several reports have suggested that STS may be of interest in the treatment of ectopic calcifications due to metabolic or inflammatory diseases (9, 10). It is also used to reduce the side effects of the cancer medication cisplatin. The authors review the presentation, diagnosis, and treatment of calciphylaxis and also describe applications of a novel therapeutic option, sodium thiosulfate. Cool the solution and add 100 ml of water and 50 ml of chloroform. Sodium thiosulfate may be used to lessen some of the side effects of cisplatin (a cancer medicine). These are not all of the side effects that may occur. If you put 130 grams in a liter jug, then add water quantity sufficient to make 1 liter, your stock solution will contain 130 grams/Liter. Persistence and degradability Sodium Thiosulfate, 1. chlorine. In animal studies, there are no teratogenic effects in offspring of . Sodium Thiosulfate is commonly used in. Sodium thiosulfate is an inactive ingredient contained in sulfacetamide ophthalmic solution which is used routinely as an otic solution delivered to the middle ear space. 3,8,9 The use of high bicarbonate dialysate may resolve sodium thiosulfate-induced metabolic acidosis.8 Because each 25 g of sodium thiosulfate in 100 mL of normal saline contains 4.8 g of sodium, the sodi um load should be considered; increases in serum sodium Two cases of advanced uremic calciphylaxis from both clinic and hospital settings are presented. Immediately discontinue PEDMARK and institute appropriate care if a hypersensitivity reaction occurs [see Dosage and Administration (2.4)] This is helping remove biofilm, inside and out. Sodium thiosulfate is also available as its pentahydrate salt (Na 2 S 2 OR 3 .5H 2 OR). Formula (search-friendly): Na2S2O35H2O. It is an industrial compound which has long been used in a wide range of medical applications, especially as an intravenous medication for . In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Transfer the resulting mixture to a separatory funnel and separate the organic layer . Sodium thiosulfate, 0.01N standardized solution is used in volumetric analysis to estimate the concentration of certain compounds in solution (hydrogen peroxide) as well as chlorine content in bleaching powder and water. sample and will neutralize up to 5 mg/L residual. MSDS Name: Sodium thiosulfate, 0.1N standard solution Catalog Numbers: AC124270000, 12427-0010 Synonyms: None. It is commonly known as an antidote to cyanide poisoning, used as an additive to bleach, and as a chemical used to test the pH of bleach products. Sodium thiosulfate (STS) is an industrial chemical which also has a long medical history. The solid is an efflorescent (loses water readily) crystalline substance that dissolves well in water. It is also a well known antidote for cyanide poisoning where the sodium thiosulfate reacts with cyanide to form sodium thiocyanate. Item Number: 705-50: Item Name: Sodium Thiosulfate Injection, USP, 12.5g/50mL, 50mL Vial: NDC: 60267-705-50: Shipping. 0N (1.0M) Persistence and degradability Not established. Sodium thiosulfate, reaction with Cyclophosphamide Cyclophosphamide or ifosfamide may be destroyed using alkaline hydrolysis in the presence of dimethylformamide or refluxing with hydrochloric acid, neutralizing, or reaction with sodium thiosulfate. These are in a 2:1 ratio. Sodium thiosulfate is used to treat cyanide poisoning. At the time of the case report, 18 months had elapsed since the . Call your doctor for medical advice about side effects. For sodium thiosulfate, the following should be .